Saturday, March 21, 2009

ANTI-PARKINSON DRUGS

Anti-Parkinson Drugs are medicines that relieve the symptoms of Parkinson's disease and other forms of Parkinsonism. PurposeAnti-Parkinson Drugs are used to treat symptoms of Parkinsonism, a group of disorders that share four main symptoms: tremor or trembling in the hands, arms, legs, jaw, and face; stiffness or rigidity of the arms, legs, and trunk; slowness of movement (Bradykinesia); and poor balance and coordination. Parkinson's disease is the most common form of Parkinsonism. Other forms of the disorder may result from viral infections, environmental toxins, carbon monoxide poisoning, and other causes. All types of Parkinsonism occur when nerve cells in a particular part of the
brain die or lose the ability to function. These cells normally produce a chemical called Dopamine, a chemical messenger that helps relay signals to different parts of the brain. This process is important in producing smooth, coordinated movement throughout the body. When Dopamine-producing cells are lost, normal movement becomes impossible. In people with late-stage Parkinson's disease, 80% or more of these important cells are dead or impaired. No cure for Parkinson's disease or other forms of Parkinsonism exists, but several drugs help relieve the symptoms. Some drugs replenish Dopamine in the brain. Others mimic the role of Dopamine or block the effects of other chemicals that cause problems in the brain when Dopamine levels drop. DescriptionThe drugs described here are of two types: Levodopa, which is used alone or in combination with Carbidopa, restores Dopamine levels in the brain. Carbidopa helps make Levodopa more effective and reduces some of the side effects that occur when Levodopa is taken by itself. Anti-Dyskinetics and Anti-Cholinergics block the effects of other brain chemicals, thereby reducing some of the involuntary tremors. All Anti- Parkinson Drugs are available only with a physician's prescription. They are sold in tablet (regular and extended-release), liquid, extended-release capsule, and injectable forms.

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